Rebecca Morelle talks to explorers of deep ocean trenches - the final frontier of exploration on Planet Earth. She meets biologists who have discovered dark realms of pink gelatinous fish and gigantic crustaceans at 8,000 metres down
Mistakes involving anthrax, deadly flu and smallpox have put high-security lab safety under the spotlight, and increased calls to limit potentially risky research
A global antibiotic resistance crisis looms but antibiotics drugs don't make pharma the profits which other medicines do. Roland Pease looks for ways to avert a medical dark age.
Our antibiotics are failing. Bacteria are developing resistance to an increasing number of the drugs that used to kill them. How bleak is the future for global health? Roland Pease looks at scientific issues behind the gathering crisis. The last new class of antibiotics was discovered in the 1980s. Are there any others in the pipeline?
In March astronomers in the BICEP2 collaboration announced they had found gravitational waves from the Big Bang. But now the evidence is being questioned. Dr Lucie Green reports.
Looking ahead to the European Space Agency's Rosetta mission - the first spacecraft to follow a comet and land a probe on its icy surface. Rosetta arrives at comet Churyumov-Gerasimenko on 6th August. It will then accompany the 4 km chunk of ice and dust close by for more than a year. In November, the craft will a drop a lander to analyse the comet's make-up and photograph the icescape. Andrew Luck-Baker talks about the mission's daring orbital manoeuvres and the big scientific questions the mission is designed to answer.
Janet Hemingway tells Jim Al-Khalili about forthcoming insecticide resistance developing in the mosquitos that transmit malaria, and how it could cost many lives.
As we grow older, it is assumed we will all become more forgetful, slower witted and much less useful members of society. Geoff Watts looks at the latest research showing this is not the case. In fact one new theory suggests older people might be slower at psychologists' intelligence tests, merely because they know more.
Jack Stewart meets the engineers inventing vehicles that drive themselves, including Google's new car without a steering wheel or pedals and Stanford University's fast moving Shelley
Peter Higgs opens up to Jim Al-Khalili, admitting that he failed to realise the full significance of the Higgs boson and a theory that later changed the face of physics.
As part of the Freedom2014 season, Entomologist Professor Adam Hart asks if what humans call free will, exists in other organisms, from chimps, all the way down to the cells in our bodies.
Gardening grandmother Ruth Brooks, also known as 'the snail lady', sets out to investigate how different animals navigate, from smell maps for cats to astronomy for newts.
Russell Foster, Professor of Circadian Neuroscience at Oxford University, is obsessed with biological clocks. He talks to Jim al-Khalili about how light controls our wellbeing.