DNA testing has for the first time confirmed the identity of the bacteria behind London's Great Plague. The plague of 1665-1666 was the last major outbreak of bubonic plague in Britain, killing nearly a quarter of London's population. It's taken a year to confirm initial findings from a suspected Great Plague burial pit during excavation work on the Crossrail site at Liverpool Street. About 3,500 burials have been uncovered during excavation of the site. Read more
Most would choose the cuddly gerbil over the much-maligned rat. But the latter's bad reputation may not be fully deserved. Central Asian rodents, not rats, prospering under warm variations in climate, could have been to blame for the arrival of the Black Death in Europe in 1347 and for repeated outbreaks of plague over the next four centuries that killed millions of people. Read more
Scientists say two of the deadliest pandemics in history were caused by strains of the same plague and warn that new versions of the bacteria could spark future outbreaks. Researchers found tiny bits of DNA in the teeth of two German victims killed by the Justinian plague about 1,500 years ago. With those fragments, they reconstructed the genome of the oldest bacteria known. Read more
The genetic code of the germ that caused the Black Death has been reconstructed by scientists for the first time. The researchers extracted DNA fragments of the ancient bacterium from the teeth of medieval corpses found in London. They say the pathogen is the ancestor of all modern plagues. Read more
County archaeologists have provided conclusive proof that the plague which wiped out about 60 per cent of the European population in the 14th century was caused by fleas. Human skeletons excavated from pits near Hereford Cathedral helped scholars at Worcestershire Historic Environment and Archaeology Service definitively confirm the plague's origins. Read more
The effects of plague on wildlife may have been underestimated in the past, according to research published today in a special issue of Vector-Borne and Zoonotic Diseases. Plague, a flea-borne bacterial disease introduced to North America in the late 1800s, spreads rapidly across a landscape, causing devastating effects to wildlife and posing risks to people. Conservation and recovery efforts for imperilled species such as the black-footed ferret and Utah prairie dog are greatly hampered by the effects of plague. Eruptions of the fatal disease have wiped out prairie dog colonies, as well as dependent ferret populations, in many locations over the years. Read more
Rare infection may have caused death of Chicago scientist A University of Chicago researcher died Sun., Sept. 13, at the Medical Centre's Bernard Mitchell Hospital from an infection which may be attributable to a weakened laboratory strain of Yersinia pestis, the bacteria that causes the plague.
The Black Death continues to cast a shadow across England. Although the modern English population is more cosmopolitan than ever, the plagues known as the Black Death killed so many people in the Middle Ages that, to this day, genetic diversity is lower in England than it was in the 11th century, according to a new analysis. Rus Hoelzel at the University of Durham, UK and his colleagues looked at the mitochondrial DNA from human remains at 4th and 11th century archaeological sites in England, and compared them to samples from the modern population stored on DNA databases such as GenBank. They found there was more variation in the ancient mitochondrial DNA sequences than in modern sequences. Hoelzel thinks random genetic drift may have lowered genetic diversity naturally. But the large unexpected drop in diversity was more likely to have been caused by population crashes following major outbreaks of the Black Death in England during the 1340s and the 1660s.