As the world is transfixed by a new H7N9 bird flu virus spreading through China, a study reminds us that a different avian influenza - H5N1 - still poses a pandemic threat. A team of scientists in China has created hybrid viruses by mixing genes from H5N1 and the H1N1 strain behind the 2009 swine flu pandemic, and showed that some of the hybrids can spread through the air between guinea pigs. The results are published in Science. Read more
New bird flu strain seen adapting to mammals, humans
A genetic analysis of the avian flu virus responsible for at least nine human deaths in China portrays a virus evolving to adapt to human cells, raising concern about its potential to spark a new global flu pandemic. The collaborative study, conducted by a group led by Masato Tashiro of the Influenza Virus Research Center, National Institute of Infectious Diseases, and Yoshihiro Kawaoka of the University of Wisconsin-Madison and the University of Tokyo, appears in the current edition (April 11, 2013) of the journal Eurosurveillance. The group examined the genetic sequences of H7N9 isolates from four of the pathogen's human victims as well as samples derived from birds and the environs of a Shanghai market. Read more
Bird flu 'could mutate to cause deadly human pandemic'
The H5N1 bird flu virus could change into a form able to spread rapidly between humans, scientists have warned. Researchers have identified five genetic changes that could allow the virus to start a deadly pandemic. Writing in the journal Science, they say it would be theoretically possible for these changes to occur in nature. Read more
The 1918 flu pandemic (the Spanish Flu) was an unusually severe and deadly influenza pandemic that spread across the world. In the United States, the flu pandemic was first observed at Haskell County, Kansas, in January 1918. On 4 March 1918, company cook Albert Gitchell reported sick at Fort Riley, Kansas. By noon on 11 March 1918, over 100 soldiers were in the hospital. Read more
Laurie Garrett: What can we learn from the 1918 flu?
Hong Kong orders chicken cull as bird flu alert raised
Hong Kong is culling 17,000 chickens after three birds were confirmed to have died from the deadly H5N1 bird flu strain in the past week. The government has banned imports and the sale of live chickens for three weeks after a chicken carcass was found at a wholesale market on Tuesday. Read more
Prime Minister Manmohan Singh Tuesday expressed concern over avian inluenza in West Bengal and directed authorities to prevent it from spreading, sources said. The directive came after India Tuesday confirmed that poultry samples from Nadia district of West Bengal tested positive for bird flu. Read more
NIH Scientists Find Earliest Known Evidence of 1918 Influenza Pandemic
Examination of lung tissue and other autopsy material from 68 American soldiers who died of respiratory infections in 1918 has revealed that the influenza virus that eventually killed 50 million people worldwide was circulating in the United States at least four months before the 1918 influenza reached pandemic levels that autumn. The study, using tissues preserved since 1918, was led by Jeffery K. Taubenberger, M.D., Ph.D., of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The researchers found proteins and genetic material from the 1918 influenza virus in specimens from 37 of the soldiers, including four who died between May and August 1918, months before the pandemic peaked. These four cases are the earliest 1918 pandemic influenza cases they know to be documented anywhere in the world, the scientists say. Read more
The 1918 flu pandemic (the Spanish Flu) was an unusually severe and deadly influenza pandemic that spread across the world. In the United States the disease was first observed at Fort Riley, Kansas, on March 4, 1918, and Queens, New York, on March 11, 1918.